How do you administer ergometrine?

Published by Charlie Davidson on

How do you administer ergometrine?

Method of administration Intramuscular injection is the recommended route. Intravenous administration of Ergometrine Injection at a dose of 250 micrograms to 500 micrograms (by slow injection) is possible, but should be limited to use only in cases of severe haemorrhage due to uterine atony.

Is ergometrine a prostaglandin?

A prostaglandin, oxytocin and ergometrine are all drugs that cause contractions of the womb (uterotonics).

Why is ergometrine given after delivery?

Ergometrine is administered after the delivery of the placenta for the purpose of contracting the uterus in order to prevent postpartum haemorrhage and postabortion haemorrhage due to uterine atony.

When do you give ergometrine?


  1. Active management of the third stage of labour. Adult: 500 mcg given with 5 units of oxytocin after delivery of the anterior shoulder or immediately after delivery of the infant.
  2. Treatment and prophylaxis of postpartum haemorrhage.
  3. Excessive uterine bleeding.
  4. Postpartum and post-abortion bleeding.

What is the side effect of Ergometrine injection?

Possible side effects include nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, tinnitus, chest pain, palpitation, bradycardia, transient hypertension and other cardiac arrhythmias, dyspnea, rashes, and shock.

What type of drug is Ergometrine?

Ergometrine is an ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. An ergot alkaloid with uterine and vascular smooth muscle contractile properties.

Is Ergometrine still used?

Ergometrine, also known as ergonovine and sold under the brand names Ergotrate, Ergostat, and Syntometrine among others, is a medication used to cause contractions of the uterus to treat heavy vaginal bleeding after childbirth….Ergometrine.

Clinical data
show IUPAC name
CAS Number 60-79-7
PubChem CID 443884

Can you give Ergometrine after Syntometrine?

If you have a multiple pregnancy (e.g. twins, triplets), Syntometrine will not be given until after the last baby has been born. Breast-feeding: The ergometrine in Syntometrine may reduce breast milk production, therefore repeated use should be avoided.

Is Ergometrine an oxytocin?

Oxytocin/ergometrine (trade name Syntometrine) is an obstetric combination drug. The components are synthetically produced oxytocin, a human hormone produced in the hypothalamus, and ergometrine, an alpha-adrenergic, dopaminergic and serotonin (5-HT2) receptor agonist. Both substances cause the uterus to contract.

What is Ergometrine drug used for?

How long does Ergometrine last for?

Effects last between 45 and 180 minutes. Common side effect include high blood pressure, vomiting, seizures, headache, and low blood pressure. Other serious side effects include ergotism. It was originally made from the rye ergot fungus but can also be made from lysergic acid.

What class of drug is Ergometrine?

Ergonovine belongs to the group of medicines known as ergot alkaloids. These medicines are usually given to stop excessive bleeding that sometimes occurs after abortion or a baby is delivered.

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