What is phosphatidylserine complex used for?

What is phosphatidylserine complex used for?

Phosphatidylserine is taken to try to prevent memory loss and mental decline that may occur as you get older. Several studies suggest that it may boost your brain power. People who took the supplement scored higher on short-term memory, mood, and concentration tests.

Is phosphatidylcholine and phosphatidylserine the same?

Phospholipids are essential components of all biological membranes. Phosphatidylcholine (PC) and Phosphatidylserine (PS) are Phosphatidyl-phospholipids that are required for normal cellular structure and function.

What is choline phosphatidylserine?

Phosphatidylcholine (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous. The phosphorous part of the phospholipid substance — the lecithin — is made up of PC.

How does phosphatidylserine act as a marker of apoptosis?

It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses.

What is the best source of phosphatidylcholine?

Dietary sources are generally in the form of phosphatidylcholine from lecithin, a type of fat. The richest dietary sources of choline include (21): Beef liver: 1 slice (2.4 ounces or 68 grams) contains 290 mg. Chicken liver: 1 slice (2.4 ounces or 68 grams) contains 222 mg.

What happens to phosphatidylserine during apoptosis?

Exposure of phosphatidylserine on the outer leaflet of the plasma membrane is a surface change common to many apoptotic cells. Normally restricted to the inner leaflet, phosphatidylserine appears as a result of decreased aminophospholipid translocase activity and activation of a calcium-dependent scramblase.

How is phosphatidylserine synthesized in the brain?

PS is synthesized from phosphatidylcholine or phosphatidylethanolamine by exchanging the base head group with serine, and this reaction is catalyzed by phosphatidylserine synthase 1 and phosphatidylserine synthase 2 located in the endoplasmic reticulum.

Is the phosphatidylserine class enriched in the plasma membrane?

Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in neural tissues.

How is PS synthesis and metabolism in the brain?

PS synthesis and metabolism in the brain. PS is synthesized by replacement of the choline group of PC by serine in a reaction catalyzed by PSS1, and also by replacement of the ethanolamine group of PE by serine in a reaction catalyzed by PSS2. These synthetic reactions occur in the endoplasmic reticulum.