Does Gemzar cause low platelets?

Published by Charlie Davidson on

Does Gemzar cause low platelets?

Poor appetite. Skin rash. Low blood counts. Your white and red blood cells and platelets may temporarily decrease.

Is Gemzar platinum based?

Gemcitabine (Gemzar) and platinum compounds have been employed as single agents, and the addition of gemcitabine to the platinums results in significant clinical benefit and response rates.

What causes platelets to be low during chemo?

The most common cause of thrombocytopenia in people with cancer is bone marrow suppression related to chemotherapy. Chemotherapy destroys rapidly dividing cells, such as those in the bone marrow which become platelets.

Is gemcitabine a strong chemo?

Drug Type: Gemcitabine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Gemcitabine is classified as an antimetabolite.

How long can you stay on Gemzar?

A cycle (dose) of gemcitabine, with paclitaxel, lasts 21 days. Gemcitabine is given on days one and eight of the cycle. The time between each cycle of treatment gives your body time to recover.

How long does Gemzar infusion take?

You have gemcitabine into your bloodstream. It takes about 30 minutes. You have the treatment through a drip into your arm or hand. A nurse puts a small tube (a cannula) into one of your veins and connects the drip to it.

What is platinum chemotherapy?

Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. They are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer.

How long can you stay on gemcitabine?

Does gemcitabine weaken the immune system?

This study shows that gemcitabine causes a profound depletion of lymphocytes. It is selectively detrimental to the humoral immune response but spares antigen-specific cellular immunity.

What are the most common side effects of Gemzar?

The most common (≥5%) Grade 3 or 4 adverse reactions were neutropenia, nausea/vomiting; increased ALT, increase alkaline phosphatase, anemia, increased AST, and thrombocytopenia. Approximately 10% of the 979 patients discontinued Gemzar due to adverse reactions.

What are the side effects of Gemzar plus cisplatin?

The incidence of febrile neutropenia (9/262 versus 2/260), sepsis (4% versus 1%), Grade 3 cardiac dysrhythmias (3% versus <1%) were all higher in the Gemzar plus cisplatin arm compared to the cisplatin alone arm.

How often does IVIG increase the platelet count?

IVIG temporarily increases the platelet count in about 80 percent of ITP patients.2 The duration of the response varies and the treatment can be repeated when the platelet count drops.

How does IVIG work for people with ITP?

Predicting Success. IVIG temporarily increases the platelet count in about 80 percent of ITP patients. 2 The duration of the response varies and the treatment can be repeated when the platelet count drops. IVIg does not work very well for those ITP patients who have anti-GPIbalpha antibodies on their platelets. 6,7.

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