How common is LCMV during pregnancy?

Several serologic studies conducted in urban areas have shown that the prevalence of LCMV antibodies in human populations range from 2% to 5%. Additionally, pregnancy-related infection has been associated with congenital hydrocephalus, chorioretinitis, and mental retardation.

How do you know if I have LCMV?

What are the Symptoms? Symptoms of LCMV infection are similar to those for influenza and include fever, stiff neck, a lack of appetite, muscle aches, headache, nausea and vomiting and occur 1–2 weeks after exposure to an infected rodent.

Does lymphocytic choriomeningitis go away on its own?

No chronic infection has been described in humans, and after the acute phase of illness, the virus is cleared from the body. However, as in all infections of the central nervous system, particularly encephalitis, temporary or permanent neurological damage is possible.

Can I be tested for LCMV?

If you have had close contact with rodents, rodent droppings, or nesting material, and/or have a fever or other symptoms of LCMV, contact your healthcare provider. A blood test can screen for an LCMV infection.

Where is LCMV most common?

LCMV infections have been reported in Europe, the Americas, Australia, and Japan, and may occur wherever infected rodent hosts of the virus are found. The disease has historically been underreported, often making it difficult to determine incidence rates or estimates of prevalence by geographic region.

How is LCMV treated?

No specific drug treatment is indicated in most cases of LCMV infection. Most patients improve spontaneously within 1-3 weeks with no sequelae. Ribavirin has in vitro activity against LCMV and has been used with success in transplant recipients with severe disease. Intravenous ribavirin is not commercially available.

How common is LCMV infection?

The disease has historically been underreported, often making it difficult to determine incidence rates or estimates of prevalence by geographic region. Several serologic studies conducted in urban areas have shown that the prevalence of LCMV antibodies in human populations range from 2% to 5%.

Does LCMV go away?

6. Are there complications after recovery? – Previous observations have shown that most patients who develop aseptic meningitis or encephalitis due to LCMV recover completely. No chronic infection has been described in humans, and after the acute phase of illness, the virus is cleared.

How long does LCMV live in mouse droppings?

Mice and hamsters can become persistently infected with LCMV if they are exposed either in utero or soon after birth. Older animals usually clear the virus completely. Persistently infected mice can shed LCMV lifelong, while hamsters may excrete it for at least 8 months.

What happens if you get LCMV during pregnancy?

However, as in all infections of the central nervous system, particularly encephalitis, temporary or permanent neurological damage is possible. Nerve deafness and arthritis have been reported. Women who become infected with LCMV during pregnancy may pass the infection on to the fetus.

Can a pregnant woman pass CMV to her fetus?

A pregnant woman can pass CMV to her fetus following primary infection, reinfection with a different CMV strain, or reactivation of a previous infection during pregnancy. Risk of transmission for primary infection is 30 to 40% in the first and second trimesters, and 40 to 70% in the third trimester.

When is the risk of CMV transmission lower?

Risk of transmission for primary infection is 30 to 40% in the first and second trimesters, and 40 to 70% in the third trimester. The risk of transmission following non-primary infection is much lower (3%).

Can you get lymphocytic choriomeningitis virus during pregnancy?

This sheet talks about exposure to lymphocytic choriomeningitis virus (LCMV) during pregnancy or while breastfeeding. This information should not take the place of medical care and advice from your healthcare provider. What is lymphocytic choriomeningitis virus (LCMV)? How is it spread?