What drugs interact with domperidone?

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What drugs interact with domperidone?

There may be an interaction between domperidone and any of the following:

  • amiodarone.
  • antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)
  • antipsychotic medications (e.g., haloperidol, pimozide, risperidone, quetiapine, ziprasidone)
  • aprepitant.
  • atropine.

What medications can reduce the absorption of some medications and nutrients in the GI system?

Medications can decrease nutrient absorption. Example: Laxatives can decrease the absorption of many vitamins and minerals. Laxatives cause food to move rapidly through the body causing poor nutrient absorption. Example: Some anticonvulsants can decrease folate absorption.

What happens if you take domperidone with food?

If you take domperidone after a meal, it will still work, but it may take longer to have an effect. Domperidone should be taken for a short period of time only. Your treatment will last no longer than seven days.

Can domperidone cause hyperkalemia?

Domperidone-associated QTc interval prolongation was correlated with hyperkalemia and serum potassium at the upper limit of normal, as well as advanced gestational age.

Who shouldnt take domperidone?

Domperidone products are contraindicated in patients with severe hepatic impairment, conditions where cardiac conduction is, or could be, impaired or where there is underlying cardiac disease such as congestive heart failure, and when co-administered with QT-prolonging medicines or potent CYP3A4 inhibitors.

Is domperidone good for acid reflux?

Domperidone is a peripheral dopamine D2-receptor antagonist that increases motility and gastric emptying [2a]. It decreases postprandial reflux time and is therefore used to treat regurgitation and vomiting.

What fruits interact with drugs?

Medicines can interact with whole fruit, fruit pulp or fruit extracts. Fruit of concern include orange, pomelo, pomegranate, cranberry, red/purple grape, apple, and grapefruit. Patients should be informed about the risk of interactions from consuming fruit.

Is domperidone bad for your heart?

Domperidone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

Does domperidone cause QT prolongation?

Background: Domperidone is a dopamine receptor antagonist used for the treatment of gastroparesis. However, it has been associated with QT prolongation, ventricular arrhythmias, and sudden cardiac death.

How long can you stay on domperidone?

How long should you take Domperidone? It is reasonable to be advised by your doctor / lactation consultant to take Domperidone for a period of up to 4 – 6 weeks. It may be several days before any increase in supply is noticed and for many women, the maximum effect may take up to 4 weeks.

Categories: Contributing